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Automatic Chemotaxis

Chemotaxis is the phenomenon in which cells, bacteria, and other cell organisms direct their movements according to certain chemicals in their immediate environment.

Examples of this phenomenon are when certain bacteria types navigate towards nutrition, and when white blood cells locate threats to the human body.


Unisensors core technology FluidScope™, which lies at the heart of the oCelloScope™ instrument, enables research within chemotaxis processes.

 

The enabling technique is the fundamental capability of tracking objects (cells) in 3 dimensions from timelapse imaging of the sample.

 

From the traces of each object information such as:

  • mean velocity
  • directedness
  • cell division rates

can be assessed for both individual cells and the population as a whole.

Distribution of track displacements
The example given here shows activated dendritic cells on a microscope slide. A drop of Fibronectin, which attracts the dendritic cells, is placed inside the ring in the top right hand corner. Both the traces of all cells indicate a tendency of moving towards the reagent and the distribution of all cells show a clear movement towards

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Unisensor's ISO 9001 and ISO 13485 certificates have been upgraded to include production.
Together with 12 international partners Unisensor now starts work on the project CELL-O-MATIC, which is funded by the EU through the 7th framework program (FP7).
Unisensor will have a booth at the DSE Fair at DTU on 28-29 March 2012. We would like to invite you to drop by and hear about what we can offer you.
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