Technology

Unisensor has developed a novel optical technology, FluidScope™, for rapid in-vitro analysis of biological fluid-based samples.

The technology handles all types of biological objects including mammalian cells, bacteria and yeast in multi- and mono- culture samples. The technology allows for both morphological differentiation between objects and monitoring of growth and mobility kinetics over time. These properties make the technology versatile and flexible compared to existing methods.

Fluidscope™

Fluidscope™ is the technology within most of Unisensor's products.

The FluidScope™ technology is based on optical sectioning in combination with a novel scanning principle (patent pending). The result is a system able to image all objects in a volume sample in optimal focus allowing for accurate morphological identification. A bi-product of this technique is the ability to extract 3D information for all objects.

Furthermore, the construction of the scanning technique facilitates an arbitrarily large sample volume, which is fundamentally limited only by the size of the sample container and the desired maximum measurement duration. As a result, it is possible to obtain high statistical accuracy for differential counting even for objects present only in low concentrations.

The high imaging speed of the FluidScope™ technology allows for monitoring the temporal behaviour of the sample by repeating the measurement periodically (time-lapse measurements). It is thus possible to extract information such as cell or bacteria mobility, morphology changes (e.g. identifying cells going into apoptosis) and growth kinetics of populations such as bacteria or yeast.

Temporal information can be extracted at up to 10 frames per second depending on the nature of the sample, which enables characterising Brownian motion of objects in the sample. The possibility of combining morphological and temporal information facilitates measurements on complex samples containing multiple types of objects while being able to distinguish objects clearly from each other.

See the Application pages to explore the optional use of the Fluidscope™ technology.

Technologies mastered

In order to exploit the full potential of the Fluidscope™ technology Unisensor need to master various technologies, which are described in more detail in the pages linked below:

Optical Innovation	This technology is fundamental in all our products.
Bioanalytical Sensors	We specialise in sensor technology based, mainly based on optical technology.
Software Development	Software is a core technology in all our products. It is used for controlling the hardware and for processing and analysing the sensor inputs.
Hardware Development	Hardware comprises electronics, mechanics and everything necessary receive and transmit the sensor signals to the software.
Patents and Publications	We have several patents registered and pending in order to protect our technology.
Research Projects	We constantly participate in a number of research projects in order to continuously stay updated on our core technologies.

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